Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells

Testosterone is indispensable for sexual development and maintaining male characteristics, and deficiency of this hormone results in primary or late-onset hypogonadism (LOH). Testosterone is primarily produced in Leydig cells, where autophagy has been reported to be extremely active. However, the fu...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Gao, Fengyi, Li, Guoping, Liu, Chao, Gao, Hui, Wang, Hao, Liu, Weixiao, Chen, Min, Shang, Yongliang, Wang, Lina, Shi, Jian, Xia, Wenlong, Jiao, Jianwei, Gao, Fei, Li, Jian, Chen, Liang, Li, Wei
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987723/
https://ncbi.nlm.nih.gov/pubmed/29618492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201710078
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