Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells

Testosterone is indispensable for sexual development and maintaining male characteristics, and deficiency of this hormone results in primary or late-onset hypogonadism (LOH). Testosterone is primarily produced in Leydig cells, where autophagy has been reported to be extremely active. However, the fu...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Gao, Fengyi, Li, Guoping, Liu, Chao, Gao, Hui, Wang, Hao, Liu, Weixiao, Chen, Min, Shang, Yongliang, Wang, Lina, Shi, Jian, Xia, Wenlong, Jiao, Jianwei, Gao, Fei, Li, Jian, Chen, Liang, Li, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987723/
https://ncbi.nlm.nih.gov/pubmed/29618492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201710078
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