Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells

Testosterone is indispensable for sexual development and maintaining male characteristics, and deficiency of this hormone results in primary or late-onset hypogonadism (LOH). Testosterone is primarily produced in Leydig cells, where autophagy has been reported to be extremely active. However, the fu...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Gao, Fengyi, Li, Guoping, Liu, Chao, Gao, Hui, Wang, Hao, Liu, Weixiao, Chen, Min, Shang, Yongliang, Wang, Lina, Shi, Jian, Xia, Wenlong, Jiao, Jianwei, Gao, Fei, Li, Jian, Chen, Liang, Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987723/
https://ncbi.nlm.nih.gov/pubmed/29618492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201710078
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