m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells

Macroautophagy/autophagy is indispensable for testosterone synthesis in Leydig cells (LCs), and here we report a negative association between m(6)A modification and autophagy in LCs during testosterone synthesis. A gradual decrease of METTL14 (methyltransferase like 14) and an increase of ALKBH5 (al...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Chen, Yabing, Wang, Jing, Xu, Dihui, Xiang, Zou, Ding, Jie, Yang, Xiaoyu, Li, Dongmei, Han, Xiaodong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007139/
https://ncbi.nlm.nih.gov/pubmed/31983283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1720431
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