m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells

Macroautophagy/autophagy is indispensable for testosterone synthesis in Leydig cells (LCs), and here we report a negative association between m(6)A modification and autophagy in LCs during testosterone synthesis. A gradual decrease of METTL14 (methyltransferase like 14) and an increase of ALKBH5 (al...

Full description

Saved in:
Bibliographic Details
Published in:Autophagy
Main Authors: Chen, Yabing, Wang, Jing, Xu, Dihui, Xiang, Zou, Ding, Jie, Yang, Xiaoyu, Li, Dongmei, Han, Xiaodong
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007139/
https://ncbi.nlm.nih.gov/pubmed/31983283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1720431
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items