Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice

WNT signaling is involved in the tumorigenesis of various cancers and regulates bone homeostasis. Palmitoleoylation of WNTs by Porcupine is required for WNT activity. Porcupine inhibitors are under development for cancer therapy. As the possible side effects of Porcupine inhibitors on bone health ar...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Endocrinol
Main Authors: Funck-Brentano, Thomas, Nilsson, Karin H, Brommage, Robert, Henning, Petra, Lerner, Ulf H, Koskela, Antti, Tuukkanen, Juha, Cohen-Solal, Martine, Movérare-Skrtic, Sofia, Ohlsson, Claes
格式: Artigo
語言:Inglês
出版: Bioscientifica Ltd 2018
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987170/
https://ncbi.nlm.nih.gov/pubmed/29720540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0153
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍