Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics

The mechanisms underlying luteolin-induced inhibition of prostate cancer (PCa) stemness have remained elusive. Here, we report that luteolin suppresses PCa stemness through Wnt signaling by upregulation of FZD6 (frizzled class receptor 6). Luteolin inhibits PCa cell proliferation, migration, self-re...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Han, Kun, Lang, Tingyuan, Zhang, Zhiqi, Zhang, Yi, Sun, Yongning, Shen, Zan, Beuerman, Roger W., Zhou, Lei, Min, Daliu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986741/
https://ncbi.nlm.nih.gov/pubmed/29867083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26761-2
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