Systematic Mapping of WNT-FZD Protein Interactions Reveals Functional Selectivity by Distinct WNT-FZD Pairs

The seven-transmembrane-spanning receptors of the FZD(1–10) class are bound and activated by the WNT family of lipoglycoproteins, thereby inducing a complex network of signaling pathways. However, the specificity of the interaction between mammalian WNT and FZD proteins and the subsequent signaling...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Dijksterhuis, Jacomijn P., Baljinnyam, Bolormaa, Stanger, Karen, Sercan, Hakki O., Ji, Yun, Andres, Osler, Rubin, Jeffrey S., Hannoush, Rami N., Schulte, Gunnar
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358105/
https://ncbi.nlm.nih.gov/pubmed/25605717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612648
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