Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation

BACKGROUND: WNT-5A signaling in the central nervous system is important for morphogenesis, neurogenesis and establishment of functional connectivity; the source of WNT-5A and its importance for cellular communication in the adult brain, however, are mainly unknown. We have previously investigated th...

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Detalhes bibliográficos
Main Authors: Halleskog, Carina, Dijksterhuis, Jacomijn Petronella, Kilander, Michaela Brita Christina, Becerril-Ortega, Javier, Villaescusa, Juan Carlos, Lindgren, Eva, Arenas, Ernest, Schulte, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458933/
https://ncbi.nlm.nih.gov/pubmed/22647544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-111
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