SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1

BACKGROUND: Cancer stem cells (CSCs) have been recognized as an important drug target, however, the underlying mechanisms have not been fully understood. SKP1 is a traditional drug target for cancer therapy, while, whether SKP1 promotes colorectal cancer (CRC) stem cells (CRC-SCs) and the underlying...

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Detalles Bibliográficos
Publicado en:Cancer Cell Int
Main Authors: Tian, Cong, Lang, Tingyuan, Qiu, Jiangfeng, Han, Kun, Zhou, Lei, Min, Daliu, Zhang, Zhiqi, Qi, Dachuan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Primary Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713163/
https://ncbi.nlm.nih.gov/pubmed/33292299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01683-0
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