N- and O-glycosylation Analysis of Human C1-inhibitor Reveals Extensive Mucin-type O-Glycosylation

Human C1-inhibitor (C1-Inh) is a serine protease inhibitor and the major regulator of the contact activation pathway as well as the classical and lectin complement pathways. It is known to be a highly glycosylated plasma glycoprotein. However, both the structural features and biological role of C1-I...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Stavenhagen, Kathrin, Kayili, H. Mehmet, Holst, Stephanie, Koeleman, Carolien A. M., Engel, Ruchira, Wouters, Diana, Zeerleder, Sacha, Salih, Bekir, Wuhrer, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986245/
https://ncbi.nlm.nih.gov/pubmed/29233911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000240
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