Site-specific N- and O-glycosylation analysis of atacicept

The Fc-fusion protein atacicept is currently under clinical investigation for its biotherapeutic application in autoimmune diseases owing to its ability to bind the two cytokines B-Lymphocyte Stimulator (BLyS) and A PRoliferation-Inducing Ligand (APRIL). Like typical recombinant IgG-based therapeuti...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Stavenhagen, Kathrin, Gahoual, Rabah, Dominguez Vega, Elena, Palmese, Angelo, Ederveen, Agnes L. Hipgrave, Cutillo, Francesca, Palinsky, Wolf, Bierau, Horst, Wuhrer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748583/
https://ncbi.nlm.nih.gov/pubmed/31349756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1630218
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