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Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Autoimmune hemolytic anemia (AIHA) is a potentially severe disease in which red blood cells (RBC) are destroyed by IgG anti-RBC autoantibodies which can lead to hemolysis. We recently found IgG Fc-glycosylation towards platelet and RBC alloantigens to be skewed towards decreased fucosylation, increa...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sonneveld, Myrthe E., de Haas, Masja, Koeleman, Carolien, de Haan, Noortje, Zeerleder, Sacha S., Ligthart, Peter C., Wuhrer, Manfred, van der Schoot, C. Ellen, Vidarsson, Gestur
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557851/
https://ncbi.nlm.nih.gov/pubmed/28811589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08654-y
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