Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G

Human immunoglobulin G (IgG) molecules are composed of two Fab portions and one Fc portion. The glycans attached to the Fc portions of IgG are known to modulate its biological activity as they influence interaction with both complement and various cellular Fc receptors. IgG glycosylation changes sig...

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Main Authors: Einarsdottir, Helga K., Selman, Maurice H. J., Kapur, Rick, Scherjon, Sicco, Koeleman, Carolien A. M., Deelder, André M., van der Schoot, C. Ellen, Vidarsson, Gestur, Wuhrer, Manfred
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552368/
https://ncbi.nlm.nih.gov/pubmed/22572841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-012-9381-6
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