Fc-Glycosylation of IgG1 is Modulated by B-cell Stimuli

We have recently shown that IgG1 directed against antigens thought to be involved in the pathogenesis of rheumatoid arthritis harbor different glycan moieties on their Fc-tail, as compared with total sera IgG1. Given the crucial roles of Fc-linked N-glycans for the structure and biological activity...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Balog, Crina I. A., Stavenhagen, Kathrin, Koeleman, Carolien A. M., Scherer, Hans Ulrich, Selman, Maurice H. J., Deelder, André M., Huizinga, Tom W. J., Toes, René E. M., Wuhrer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Regular Issue
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098587/
https://ncbi.nlm.nih.gov/pubmed/21372248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.004655
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