Low anti-RhD IgG-Fc-fucosylation in pregnancy: a new variable predicting severity in haemolytic disease of the fetus and newborn

Haemolytic disease of the fetus and newborn (HDFN) may occur when maternal IgG antibodies against red blood cells (RBCs), often anti-RhD (anti-D) antibodies, cross the placenta and mediate the destruction of RBCs via phagocytic IgG-Fc-receptors (FcγR). Clinical severity is not strictly related to ti...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Kapur, Rick, Della Valle, Luciana, Sonneveld, Myrthe, Hipgrave Ederveen, Agnes, Visser, Remco, Ligthart, Peter, de Haas, Masja, Wuhrer, Manfred, van der Schoot, C Ellen, Vidarsson, Gestur
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Transfusion
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282073/
https://ncbi.nlm.nih.gov/pubmed/24909983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12965
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