Low anti-RhD IgG-Fc-fucosylation in pregnancy: a new variable predicting severity in haemolytic disease of the fetus and newborn

Haemolytic disease of the fetus and newborn (HDFN) may occur when maternal IgG antibodies against red blood cells (RBCs), often anti-RhD (anti-D) antibodies, cross the placenta and mediate the destruction of RBCs via phagocytic IgG-Fc-receptors (FcγR). Clinical severity is not strictly related to ti...

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Bibliografiske detaljer
Udgivet i:Br J Haematol
Main Authors: Kapur, Rick, Della Valle, Luciana, Sonneveld, Myrthe, Hipgrave Ederveen, Agnes, Visser, Remco, Ligthart, Peter, de Haas, Masja, Wuhrer, Manfred, van der Schoot, C Ellen, Vidarsson, Gestur
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Transfusion
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282073/
https://ncbi.nlm.nih.gov/pubmed/24909983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12965
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