Low anti-RhD IgG-Fc-fucosylation in pregnancy: a new variable predicting severity in haemolytic disease of the fetus and newborn

Haemolytic disease of the fetus and newborn (HDFN) may occur when maternal IgG antibodies against red blood cells (RBCs), often anti-RhD (anti-D) antibodies, cross the placenta and mediate the destruction of RBCs via phagocytic IgG-Fc-receptors (FcγR). Clinical severity is not strictly related to ti...

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Detalles Bibliográficos
Publicado en:Br J Haematol
Autores principales: Kapur, Rick, Della Valle, Luciana, Sonneveld, Myrthe, Hipgrave Ederveen, Agnes, Visser, Remco, Ligthart, Peter, de Haas, Masja, Wuhrer, Manfred, van der Schoot, C Ellen, Vidarsson, Gestur
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Transfusion
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282073/
https://ncbi.nlm.nih.gov/pubmed/24909983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12965
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