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Bmp2 controls iron homeostasis in mice independent of Bmp6

Hepcidin is a key iron regulatory hormone that controls expression of the iron exporter ferroportin to increase the iron supply when needed to support erythropoiesis and other essential functions, but to prevent the toxicity of iron excess. The bone morphogenetic protein (BMP)-SMAD signaling pathway...

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Detalles Bibliográficos
Publicado en:Am J Hematol
Autores principales: Canali, Susanna, Wang, Chia-Yu, Zumbrennen-Bullough, Kimberly B., Bayer, Abraham, Babitt, Jodie L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986189/
https://ncbi.nlm.nih.gov/pubmed/28815688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24888
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