NetSig: network-based discovery from cancer genomes

Approaches that integrate molecular network information and tumor genome data could complement gene-based statistical tests to identify likely new cancer genes, but are challenging to validate at scale and their predictive value remains unclear. We developed a robust statistic (NetSig) that integrat...

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Vydáno v:Nat Methods
Hlavní autoři: Horn, Heiko, Lawrence, Michael S., Chouinard, Candace R., Shrestha, Yashaswi, Hu, Jessica Xin, Worstell, Elizabeth, Shea, Emily, Ilic, Nina, Kim, Eejung, Kamburov, Atanas, Kashani, Alireza, Hahn, William C., Campbell, Joshua D., Boehm, Jesse S., Getz, Gad, Lage, Kasper
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985961/
https://ncbi.nlm.nih.gov/pubmed/29200198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4514
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