NetSig: network-based discovery from cancer genomes

Approaches that integrate molecular network information and tumor genome data could complement gene-based statistical tests to identify likely new cancer genes, but are challenging to validate at scale and their predictive value remains unclear. We developed a robust statistic (NetSig) that integrat...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Horn, Heiko, Lawrence, Michael S., Chouinard, Candace R., Shrestha, Yashaswi, Hu, Jessica Xin, Worstell, Elizabeth, Shea, Emily, Ilic, Nina, Kim, Eejung, Kamburov, Atanas, Kashani, Alireza, Hahn, William C., Campbell, Joshua D., Boehm, Jesse S., Getz, Gad, Lage, Kasper
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985961/
https://ncbi.nlm.nih.gov/pubmed/29200198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4514
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