Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice

The complement system, composed of the three activation pathways, has both protective and pathogenic roles in the development of systemic lupus erythematosus (or lupus), a prototypic autoimmune disease. The classical pathway contributes to the clearance of immune complexes (ICs) and apoptotic cells,...

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Publicado en:Front Immunol
Autores principales: Machida, Takeshi, Sakamoto, Natsumi, Ishida, Yumi, Takahashi, Minoru, Fujita, Teizo, Sekine, Hideharu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985374/
https://ncbi.nlm.nih.gov/pubmed/29892304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01191
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