Mechanisms of Mannose-Binding Lectin-Associated Serine Proteases-1/3 Activation of the Alternative Pathway of Complement

Mannose-binding lectin-associated serine proteases-1/3 (MASP-1/3) are essential in activating the alternative pathway (AP) of complement through cleaving pro-factor D (pro-Df) into mature Df. MASP are believed to require binding to mannose binding lectins (MBL) or ficolins (FCN) to carry out their b...

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Detalhes bibliográficos
Main Authors: Banda, Nirmal K., Takahashi, Minoru, Takahashi, Kazue, Stahl, Gregory L., Hyatt, Stephanie, Glogowska, Magdalena, Wiles, Timothy A., Endo, Yuichi, Fujita, Teizo, Holers, V. Michael, Arend, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226714/
https://ncbi.nlm.nih.gov/pubmed/21943708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.08.021
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