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Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D
The complement system is an essential component of innate immunity, participating in the pathogenesis of inflammatory diseases and in host defense. In the lectin complement pathway, mannose-binding lectin (MBL) and ficolins act as recognition molecules, and MBL-associated serine protease (MASP) is a...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812541/ https://ncbi.nlm.nih.gov/pubmed/20038603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090633 |
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