Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

The complement system is an essential component of innate immunity, participating in the pathogenesis of inflammatory diseases and in host defense. In the lectin complement pathway, mannose-binding lectin (MBL) and ficolins act as recognition molecules, and MBL-associated serine protease (MASP) is a...

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Detalles Bibliográficos
Autores principales: Takahashi, Minoru, Ishida, Yumi, Iwaki, Daisuke, Kanno, Kazuko, Suzuki, Toshiyuki, Endo, Yuichi, Homma, Yoshimi, Fujita, Teizo
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812541/
https://ncbi.nlm.nih.gov/pubmed/20038603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090633
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