Deconstructing the lectin pathway in the pathogenesis of experimental inflammatory arthritis: essential role of the lectin ficolin B and mannose-binding protein-associated serine protease 2

Complement plays an important role in the pathogenesis of rheumatoid arthritis (RA). While the alternative pathway (AP) is known to play a key pathogenic role in models of RA, the importance of the lectin pathway (LP) pattern recognition molecules such as ficolin A (FCN A), ficolin B (FCN B) and col...

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Bibliographic Details
Published in:J Immunol
Main Authors: Banda, Nirmal K., Acharya, Sumitra, Scheinman, Robert I., Mehta, Gaurav, Takahashi, Minoru, Endo, Yuichi, Zhou, Wuding, Farrar, Conrad A., Sacks, Steven H., Fujita, Teijo, Sekine, Hideharu, Holers, V. Michael
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568486/
https://ncbi.nlm.nih.gov/pubmed/28739878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700119
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