IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells

Natural killer (NK) cells are innate lymphocytes that play essential roles in mediating antitumor immunity. NK cells respond to various inflammatory stimuli including cytokines and stress-induced cellular ligands which activate germline-encoded activation receptors (NKRs), such as NKG2D. The signali...

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Publicado en:Front Immunol
Main Authors: Abel, Alex M., Tiwari, Aradhana A., Gerbec, Zachary J., Siebert, Jason R., Yang, Chao, Schloemer, Nathan J., Dixon, Kate J., Thakar, Monica S., Malarkannan, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985319/
https://ncbi.nlm.nih.gov/pubmed/29892299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01168
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