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IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells

Natural killer (NK) cells are innate lymphocytes that play essential roles in mediating antitumor immunity. NK cells respond to various inflammatory stimuli including cytokines and stress-induced cellular ligands which activate germline-encoded activation receptors (NKRs), such as NKG2D. The signali...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Abel, Alex M., Tiwari, Aradhana A., Gerbec, Zachary J., Siebert, Jason R., Yang, Chao, Schloemer, Nathan J., Dixon, Kate J., Thakar, Monica S., Malarkannan, Subramaniam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985319/
https://ncbi.nlm.nih.gov/pubmed/29892299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01168
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