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The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast

By altering the dynamics of DNA replication and repair, alternative ploidy states may experience different rates and types of new mutations, leading to divergent evolutionary outcomes. We report a direct comparison of the genome-wide spectrum of spontaneous mutations arising in haploids and diploids...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sharp, Nathaniel P., Sandell, Linnea, James, Christopher G., Otto, Sarah P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984525/
https://ncbi.nlm.nih.gov/pubmed/29760081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801040115
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