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Precise estimates of mutation rate and spectrum in yeast
Mutation is the ultimate source of genetic variation. The most direct and unbiased method of studying spontaneous mutations is via mutation accumulation (MA) lines. Until recently, MA experiments were limited by the cost of sequencing and thus provided us with small numbers of mutational events and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050626/ https://ncbi.nlm.nih.gov/pubmed/24847077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323011111 |
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