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Extremely Rare Polymorphisms in Saccharomyces cerevisiae Allow Inference of the Mutational Spectrum

The characterization of mutational spectra is usually carried out in one of three ways–by direct observation through mutation accumulation (MA) experiments, through parent-offspring sequencing, or by indirect inference from sequence data. Direct observations of spontaneous mutations with MA experime...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Zhu, Yuan O., Sherlock, Gavin, Petrov, Dmitri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207638/
https://ncbi.nlm.nih.gov/pubmed/28046117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006455
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