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The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast

By altering the dynamics of DNA replication and repair, alternative ploidy states may experience different rates and types of new mutations, leading to divergent evolutionary outcomes. We report a direct comparison of the genome-wide spectrum of spontaneous mutations arising in haploids and diploids...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sharp, Nathaniel P., Sandell, Linnea, James, Christopher G., Otto, Sarah P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984525/
https://ncbi.nlm.nih.gov/pubmed/29760081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801040115
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