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The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast

By altering the dynamics of DNA replication and repair, alternative ploidy states may experience different rates and types of new mutations, leading to divergent evolutionary outcomes. We report a direct comparison of the genome-wide spectrum of spontaneous mutations arising in haploids and diploids...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Sharp, Nathaniel P., Sandell, Linnea, James, Christopher G., Otto, Sarah P.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984525/
https://ncbi.nlm.nih.gov/pubmed/29760081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801040115
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