FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system

Disrupted in schizophrenia 1 (DISC1) is a multi-functional scaffolding protein that has been associated with neuropsychiatric disease. The role of DISC1 is to assemble protein complexes that promote neural development and signaling, hence tight control of the concentration of cellular DISC1 in neuro...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Yalla, K, Elliott, C, Day, J P, Findlay, J, Barratt, S, Hughes, Z A, Wilson, L, Whiteley, E, Popiolek, M, Li, Y, Dunlop, J, Killick, R, Adams, D R, Brandon, N J, Houslay, M D, Hao, B, Baillie, G S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984089/
https://ncbi.nlm.nih.gov/pubmed/28727686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.138
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