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FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system
Disrupted in schizophrenia 1 (DISC1) is a multi-functional scaffolding protein that has been associated with neuropsychiatric disease. The role of DISC1 is to assemble protein complexes that promote neural development and signaling, hence tight control of the concentration of cellular DISC1 in neuro...
Kaydedildi:
Yayımlandı: | Mol Psychiatry |
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Nature Publishing Group
2018
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984089/ https://ncbi.nlm.nih.gov/pubmed/28727686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.138 |
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