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Exploiting Botulinum Neurotoxins for the Study of Brain Physiology and Pathology

Botulinum neurotoxins are metalloproteases that specifically cleave N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins in synaptic terminals, resulting in a potent inhibition of vesicle fusion and transmitter release. The family comprises different serotypes (BoNT/A to Bo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Toxins (Basel)
Hauptverfasser: Caleo, Matteo, Restani, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983231/
https://ncbi.nlm.nih.gov/pubmed/29693600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10050175
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