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Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain
Activation of RAF kinase involves the association of its RAS-binding domain (RBD) and cysteine-rich domain (CRD) with membrane-anchored RAS. However, the overall architecture of the RAS/RBD/CRD ternary complex and the orientations of its constituent domains at the membrane remain unclear. Here, we h...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5981303/ https://ncbi.nlm.nih.gov/pubmed/29855542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26832-4 |
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