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A Phage Lysin Fused to a Cell-Penetrating Peptide Kills Intracellular Methicillin-Resistant Staphylococcus aureus in Keratinocytes and Has Potential as a Treatment for Skin Infections in Mice

Staphylococcus aureus is the main pathogen that causes skin and skin structure infections and is able to survive and persist in keratinocytes of the epidermis. Since the evolution of multidrug-resistant bacteria, the use of phages and their lysins has presented a promising alternative approach to tr...

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Dades bibliogràfiques
Publicat a:Appl Environ Microbiol
Autors principals: Wang, ZhaoFei, Kong, LiCheng, Liu, Yang, Fu, Qiang, Cui, ZeLin, Wang, Jian, Ma, JingJiao, Wang, HengAn, Yan, YaXian, Sun, JianHe
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981068/
https://ncbi.nlm.nih.gov/pubmed/29625989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00380-18
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