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A Phage Lysin Fused to a Cell-Penetrating Peptide Kills Intracellular Methicillin-Resistant Staphylococcus aureus in Keratinocytes and Has Potential as a Treatment for Skin Infections in Mice

Staphylococcus aureus is the main pathogen that causes skin and skin structure infections and is able to survive and persist in keratinocytes of the epidermis. Since the evolution of multidrug-resistant bacteria, the use of phages and their lysins has presented a promising alternative approach to tr...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Wang, ZhaoFei, Kong, LiCheng, Liu, Yang, Fu, Qiang, Cui, ZeLin, Wang, Jian, Ma, JingJiao, Wang, HengAn, Yan, YaXian, Sun, JianHe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981068/
https://ncbi.nlm.nih.gov/pubmed/29625989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00380-18
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