Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration

Spermidine has therapeutic effects in many diseases including as heart diastolic function, myopathic defects and neurodegenerative disorders via autophagy activation. Autophagy has been found to mitigate cell apoptosis in intervertebral disc degeneration (IDD). Accordingly, we theorize that spermidi...

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書目詳細資料
發表在:J Cell Mol Med
Main Authors: Zheng, Zengming, Wang, Zhou‐Guang, Chen, Yu, Chen, Jian, Khor, Sinan, Li, Jiawei, He, Zili, Wang, Qingqing, Zhang, Hongyu, Xu, Ke, Fanghua, Gong, Xiao, Jian, Wang, Xiangyang
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980193/
https://ncbi.nlm.nih.gov/pubmed/29575654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13586
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