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Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog

The over two dozen CYP2B structures of human, rabbit, and woodrat enzymes solved in the last decade have significantly enhanced our understanding of the structure-function relationships of drug metabolizing enzymes. More recently, an important role has emerged for halogen-π interactions in the CYP2B...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Shah, Manish B., Zhang, Qinghai, Halpert, James R.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979536/
https://ncbi.nlm.nih.gov/pubmed/29596329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041025
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