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Functional Characterization of Novel Atrial Fibrillation-Linked GJA5 (Cx40) Mutants

Atrial fibrillation (AF) is the most common form of cardiac arrhythmia. Recently, four novel heterozygous Cx40 mutations—K107R, L223M, Q236H, and I257L—were identified in 4 of 310 unrelated AF patients and a followup genetic analysis of the mutant carriers’ families showed that the mutants were pres...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Noureldin, Mahmoud, Chen, Honghong, Bai, Donglin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979441/
https://ncbi.nlm.nih.gov/pubmed/29587382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040977
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