A Dominant Loss-of-Function GJA1 (Cx43) Mutant Impairs Parturition in the Mouse

Expression of GJA1 (commonly known as connexin43 or Cx43), a major myometrial gap junction protein, is upregulated before the onset of delivery, suggesting an essential role for Cx43-mediated gap junctional intercellular communication (GJIC) in normal uterine contraction during parturition. To deter...

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Bibliographic Details
Main Authors: Tong, Dan, Lu, Xuerong, Wang, Hong-Xing, Plante, Isabelle, Lui, Ed, Laird, Dale W., Bai, Donglin, Kidder, Gerald M.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849809/
https://ncbi.nlm.nih.gov/pubmed/19176884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.071969
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