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Altered conductance and permeability of Cx40 mutations associated with atrial fibrillation

Gap junctions ensure the rapid propagation of the action potential throughout the myocardium. Three mutant forms of connexin40 (Cx40; A96S, M163V, and G38D), the primary component of the atrial gap junction channel, are associated with atrial fibrillation and retain the ability to form functional ch...

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Bibliografske podrobnosti
izdano v:J Gen Physiol
Main Authors: Santa Cruz, Ana, Meşe, Gülistan, Valiuniene, Laima, Brink, Peter R., White, Thomas W., Valiunas, Virginijus
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621748/
https://ncbi.nlm.nih.gov/pubmed/26503720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511475
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