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Connexin26 deafness associated mutations show altered permeability to large cationic molecules
Intercellular communication is important for cochlear homeostasis because connexin26 (Cx26) mutations are the leading cause of hereditary deafness. Gap junctions formed by different connexins have unique selectivity to large molecules, so compensating for the loss of one isoform can be challenging i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575827/ https://ncbi.nlm.nih.gov/pubmed/18684989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00008.2008 |
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