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Degradation of a Connexin40 mutant linked to atrial fibrillation is accelerated

Several Cx40 mutants have been identified in patients with atrial fibrillation (AF). We have been working to identify physiological or cell biological abnormalities of several these human mutants that might explain how they contribute to disease pathogenesis. Wild type (wt) Cx40 or four different mu...

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Detalles Bibliográficos
Main Authors: Gemel, Joanna, Simon, Adria R., Patel, Dakshesh, Xu, Qin, Matiukas, Arvydas, Veenstra, Richard D., Beyer, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135452/
https://ncbi.nlm.nih.gov/pubmed/24973497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.06.010
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