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Atrial fibrillation-associated Connexin40 mutants make hemichannels and synergistically form gap junction channels with novel properties
Mutations of Cx40 (GJA5) have been identified in people with lone chronic atrial fibrillation including G38D and M163V which were found in the same patient. We used dual whole cell patch clamp procedures to examine the transjunctional voltage (V(j)) gating and channel conductance properties of these...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989446/ https://ncbi.nlm.nih.gov/pubmed/24457199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.01.010 |
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