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Direct Observation of the Oxidation of DNA Bases by Phosphate Radical Formed under Radiation: A Model of Backbone-to-base Hole Transfer

In irradiated DNA, by base-to-base and backbone-to-base hole transfer processes, the hole (i.e., the unpaired spin) localizes on the most electropositive base, guanine. Phosphate radicals formed via ionization events in DNA-backbone must play an important role in the backbone-to-base hole transfer p...

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Detalhes bibliográficos
Publicado no:Phys Chem Chem Phys
Main Authors: Jun, MA, Marignier, Jean-Louis, Pernot, Pascal, Houée-Levin, Chantal, Kumar, Anil, Sevilla, Michael D., Adhikary, Amitava, Mostafavi, Mehran
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976554/
https://ncbi.nlm.nih.gov/pubmed/29786710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cp00352a
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