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Direct Formation of the C5′-Radical in the Sugar-Phosphate Backbone of DNA by High Energy Radiation
Neutral sugar radicals formed in DNA sugar-phosphate backbone are well-established as precursors of biologically important damage such as DNA-strand scission and crosslinking. In this work, we present electron spin resonance (ESR) evidence showing that the sugar radical at C5′ (C5′•) is one of the m...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360814/ https://ncbi.nlm.nih.gov/pubmed/22553971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp3023919 |
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