Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy

BACKGROUND: Malignant pleural mesothelioma (MPM) is a biologically highly aggressive tumor arising from the pleura with a dismal prognosis. Cisplatin is the drug of choice for the treatment of MPM, and carboplatin seems to have comparable efficacy. Nevertheless, cisplatin treatment results in a resp...

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Udgivet i:Oncotarget
Main Authors: Mairinger, Fabian D., Schmeller, Jan, Borchert, Sabrina, Wessolly, Michael, Mairinger, Elena, Kollmeier, Jens, Hager, Thomas, Mairinger, Thomas, Christoph, Daniel C., Walter, Robert F.H., Eberhardt, Wilfried E.E., Plönes, Till, Wohlschlaeger, Jeremias, Jasani, Bharat, Schmid, Kurt Werner, Bankfalvi, Agnes
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
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Research Paper: Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976462/
https://ncbi.nlm.nih.gov/pubmed/29854276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24962
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