Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma

Malignant pleural mesothelioma (MPM) is a rare, but aggressive tumor with dismal prognosis. Platinum-based chemotherapy is regularly used as part of multimodality therapy. The expression of metallothioneins (MT) has been identified as a reason for cisplatin resistance, which often leads to early the...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Borchert, Sabrina, Suckrau, Pia-Maria, Walter, Robert F. H., Wessolly, Michael, Mairinger, Elena, Steinborn, Julia, Hegedus, Balazs, Hager, Thomas, Herold, Thomas, Eberhardt, Wilfried E. E., Wohlschlaeger, Jeremias, Aigner, Clemens, Bankfalvi, Agnes, Schmid, Kurt Werner, Mairinger, Fabian D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596082/
https://ncbi.nlm.nih.gov/pubmed/33122816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75807-x
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