Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy

BACKGROUND: Malignant pleural mesothelioma (MPM) is a biologically highly aggressive tumor arising from the pleura with a dismal prognosis. Cisplatin is the drug of choice for the treatment of MPM, and carboplatin seems to have comparable efficacy. Nevertheless, cisplatin treatment results in a resp...

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Vydáno v:Oncotarget
Hlavní autoři: Mairinger, Fabian D., Schmeller, Jan, Borchert, Sabrina, Wessolly, Michael, Mairinger, Elena, Kollmeier, Jens, Hager, Thomas, Mairinger, Thomas, Christoph, Daniel C., Walter, Robert F.H., Eberhardt, Wilfried E.E., Plönes, Till, Wohlschlaeger, Jeremias, Jasani, Bharat, Schmid, Kurt Werner, Bankfalvi, Agnes
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper: Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976462/
https://ncbi.nlm.nih.gov/pubmed/29854276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24962
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